Maria Matala was born on 29 January 1959 in Athens, her origins from Sparta, Peloponnese and Istanbul, Asia Minor. She graduated from Pierce College in 1976, and studied English Literature at Deree College (1976-1977) and French Literature at the University of Athens (1980-1984). She obtained a Diploma of Spanish Studies (1985) and a DEA in Comparative Literature from the University of Picardy in France (1987). She received the Grand Prix Européen des Arts et des Lettres, France (1990). Parallel to her studies in literature Matala had been sent by Nico Hadjikyriaco-Ghika to Thanassis Stefopoulos' painting workshop (1994-2005). Later, she studied with George Pastakas and Louisa Delfi.
Matala has presented the following personal exhibitions: Le Ver Lisant, France (2004); Greek-French Association, Athens (2005); Municipal Gallery of Corinth (2007); and Maria Matala: Afternoons, Art Gallery Café, Voula (2008). She has also participated in the following group exhibitions: Athinaïko Steki, Athens (1994); Pierce College Alumni Artists, House of Cyprus, Athens (1995); A Tribute to the Alumnae Artists of Pierce College, Cultural Centre of The American College of Greece, Plaka (2006); Cultural Center of the Municipality of Voula (2006); UNESCO Artists, Municipal Gallery of Piraeus (2007); and Sofitel Athens Airport Hotel, Spata (2007). Works of Maria Matala are kept at following public institutions: The American College of Greece; and the Municipal Gallery of Corinth.
Maria Matala continues to live and work in Athens.